New optical coherence tomography biomarker for diagnosis of acute optic neuritis in multiple sclerosis.

ABSTRACT:

Objectives

Is imaging of retrolaminar optic nerve, during attack of acute optic neuritis in multiple sclerosis valuable?

Methods

This is a prospective observational Case series study. Twenty two patients recruited from Al-Azhar University Hospitals and Charity Eye Centre (El-Mustafa Eye Centre, Cairo); from October 2022 to February 2024. The patients were referred; as, they had developed episode of acute optic neuritis. Full ophthalmic and neurological examinations were done for all patients within 2 weeks of acute optic neuritis. Imaging of peripapillary retinal nerve fiber layer by conventional spectral domain optical coherence tomography (OCT), and retrolaminar part of optic nerve by enhanced depth imaging OCT were done for both acute optic neuritis eyes and the fellow ey

SUBMITTER: Safwat HM 

PROVIDER: S-EPMC11835559 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature