Prognostic value of circulating Chromogranin A in prostate cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

There are discrepancies between the results of different studies regarding the prognostic role of circulating Chromogranin A (CgA) in prostate cancer. Therefore, we conducted a meta-analysis of the available findings to explore the value of circulating Chromogranin A in the prognosis of prostate cancer.

Methods

We systematically searched the PubMed, Embase, Web of Science, Cochrane Library, and Clinical Trials databases for studies on the relationship between CgA and survival outcomes in prostate cancer from inception until December 2024, and we focused on articles detecting circulating CgA, with the primary endpoints of the studies being overall survival (OS), and progression-free survival (PFS).

Results

Of the 2049 articles retrieved, 10 articles met our

SUBMITTER: Tang X 

PROVIDER: S-EPMC11835686 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature