Drug utilization study of antiparkinsonian medication in Romania during 25 years.

ABSTRACT:

Background

Antiparkinsonian medication has significantly evolved over the last 2 decades, offering various pharmacologic approaches. The aim of this study was to explore the trends and to determine the statistical significance of the observed changes in the antiparkinsonian medication utilization in Romania during 1998-2022.

Methods

This antiparkinsonian drug utilization study used data provided by CEGEDIM Romania, originating from the Pharma and Hospital Report. Quantitative data for each ATC N04 antiparkinsonian medication were converted to total defined daily doses (DDDs) and to DDD/1000inhabitants/day (DDD/TID). The autoregressive integrated moving average (ARIMA) model was employed to determine the statistical significance of the observed changes in the trends of antipa

SUBMITTER: Bucsa C 

PROVIDER: S-EPMC11835688 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature