Analyzing the correlation between acute ischemic stroke and triglyceride-glucose index based on ordered logistic regression.

ABSTRACT:

Objective

To investigate the association between insulin resistance, measured by the triglyceride-glucose (TyG) index, and clinical outcomes in patients with acute ischemic stroke who underwent intravenous thrombolysis with alteplase.

Methods

This retrospective study included 165 patients with acute ischemic stroke treated with intravenous alteplase. Insulin resistance was evaluated using the TyG index, and its relationship with the modified Rankin Scale (mRS) scores was analyzed. The analysis was conducted using R software (version R 4.1.3) to evaluate the correlation between the TyG index and functional outcomes at 14, 30, and 90 days post-stroke.

Results

The study found that each unit increase in the TyG index significantly raised the risk of poor functional outcom

SUBMITTER: He L 

PROVIDER: S-EPMC11835692 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature