Predictive value of neutrophil to lymphocyte ratio for the clinical outcomes of acquired immune deficiency syndrome: a systematic review and meta-analysis.

ABSTRACT:

Objective

This study aimed to explore the predictive value of the neutrophil-to-lymphocyte ratio (NLR) for outcomes in Acquired Immune Deficiency Syndrome (AIDS) patients.

Methods

PubMed, Embase, Cochrane, and Web of Science were conducted to search literature up to May 2024 and cohort and case-control studies were included. The primary outcomes were mortality and progression-free survival (PFS). Pooled odds ratios (ORs) or hazard ratios (HRs) with 95% confidence intervals (CIs) were calculated using a random-effects model. We conducted sensitivity analyses to assess result stability, reliability, and subgroup analyses to identify sources of heterogeneity using Review Manager 5.4.1. Egger's tests were performed with Stata 15.1, and funnel plots were generated using Review Ma

SUBMITTER: Guo F 

PROVIDER: S-EPMC11835827 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature