Pediatric bacterial meningitis in southern China: analysis of 838 cases.

ABSTRACT:

Objective

This work aims to study the clinical features and risk factors of children with bacterial meningitis (BM) in southern China.

Methods

Clinical data of children with BM between 2012 and 2018 from one national center were analyzed retrospectively.

Results

A total of 838 patients (male/female = 1.8:1) were enrolled, with 90.6% under 1 year old. Common symptoms included fever, seizure, lethargy, vomiting, anorexia, poor feeding, and irritability. Most patients initially exhibited typical cerebrospinal fluid (CSF) changes of BM, including elevated white blood cell count, increased protein levels, and decreased glucose concentration. Some initially atypical cases showed typical changes after about 1 week. Furthermore, 38.7% of the patients had positive bacterial cu

SUBMITTER: Chen L 

PROVIDER: S-EPMC11835870 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature