Effects of plant active substances in rheumatoid arthritis-a systematic review and network meta-analysis.

ABSTRACT:

Background

Plant active substances are extensively utilized in treating rheumatoid arthritis (RA). Despite numerous experimental and clinical studies on plant active substances their efficacy remains largely unsubstantiated. The widespread use of these extracts as therapeutic measures for RA is problematic due to the lack of compelling evidence.

Objective

Our research aims to assess the impact of plant active substances on RA by conducting a network meta-analysis.

Methods

We systematically searched four electronic databases-PubMed, EMBASE, the Cochrane Central Register of Controlled Trials, and Web of Science-from their inception to August 2024. The main focus was on assessing primary outcomes, including the Visual Analogue Scale (VAS), inflammatory markers, Swollen J

SUBMITTER: Peng Q 

PROVIDER: S-EPMC11835909 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature