Dissecting the rising tide of inflammatory bowel disease among youth in a changing world: insights from GBD 2021.

ABSTRACT:

Objectives

This study investigates the alarming epidemiological trends of inflammatory bowel disease (IBD) among children and young adults, highlighting the associated disease burden on global health.

Materials and methods

Utilizing data from the Global Burden of Disease (GBD) study 2021, we conducted a comprehensive analysis of age-standardized incidence rates (ASIR), age-standardized mortality rates (ASMR), disability-adjusted life years (DALYs), and estimated annual percentage changes (EAPC). Future trends were forecasted using the Bayesian age-period-cohort model.

Results

From 1990 to 2021, IBD incidence and DALY rates remained persistently high, with a concerning upward trend noted among children and young adults. While men experienced a decline in DALY rates, wo

SUBMITTER: Chen L 

PROVIDER: S-EPMC11836149 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature