The value of contrast-enhanced ultrasound in assessing carotid plaque vulnerability and predicting stroke risk.

ABSTRACT: The presence of vulnerable carotid plaques plays a critical role in ischemic stroke pathogenesis, with intraplaque neovascularization (IPN) serving as a key indicator of plaque instability. Contrast-enhanced ultrasound (CEUS) provides a comprehensive evaluation of both plaque surface morphology and microvascular features. This study assesses the utility of CEUS in identifying vulnerable carotid plaques, quantifying IPN, and predicting stroke risk. The study involved 91 patients with carotid stenosis who underwent carotid endarterectomy (CEA). Preoperative assessments included CEUS and high-resolution magnetic resonance imaging (HR-MRI). Following surgery, plaque samples were collected and subjected to pathological analysis. CEUS offered comprehensive morphological insights, categorizing pl

SUBMITTER: Cao J 

PROVIDER: S-EPMC11836186 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature