Prevalence and risk of complications in untreated patients with adult growth hormone deficiency.

ABSTRACT:

Purpose

Adult growth hormone deficiency (AGHD) increases the prevalence of complications, including metabolic disorder, leading to increased cardiovascular mortality from cardiovascular diseases. However, no large database studies have evaluated AGHD patients without GH replacement therapy (GHRT). We investigated the prevalence of AGHD-related complications in patients without GHRT.

Methods

Patients with AGHD and associated complications were identified from the Medical Data Vision claims database using Japanese local disease codes mapped to ICD-10 codes. The prevalence of AGHD-related complications in 2020 was estimated to compare with the prevalence in the Japanese general population in the latest available year 2020. Risk factors for complications were evaluated by Kaplan

SUBMITTER: Fukuoka H 

PROVIDER: S-EPMC11836217 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature