Placental quantitative susceptibility mapping and T2* characteristics for predicting birth weight in healthy and high-risk pregnancies.

ABSTRACT:

Background

The human placenta is critical in supporting fetal development, and placental dysfunction may compromise maternal-fetal health. Early detection of placental dysfunction remains challenging due to the lack of reliable biomarkers. This study compares placental quantitative susceptibility mapping and T2* values between healthy and high-risk pregnancies and investigates their association with maternal and fetal parameters and their ability to predict birth weight (BW).

Methods

A total of 105 pregnant individuals were included: 68 healthy controls and 37 high-risk due to fetal growth restriction (FGR), chronic or gestational hypertension, and pre-eclampsia. Placental magnetic resonance imaging data were collected using a three-dimensional multi-echo radiofrequency-spoi

SUBMITTER: Pishghadam M 

PROVIDER: S-EPMC11836258 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature