Additive manufacturing of water-soluble 3D micro molds for complex-shaped lipid microparticles.

ABSTRACT: Micro and nanoparticles made from polymers, metals, ceramics, and lipids are crucial for biomedical devices, energy storage, and electronics. Traditional fabrication methods like grinding, milling, and emulsification result in monolithic shapes and heterogeneous sizes. To improve shape control, techniques such as photolithography, inkjet printing (IJP), and molding are employed. Water-soluble molds are particularly promising for materials with solvent incompatibility, thermolability, and poor mechanical properties. Among them, lipids are interesting for their use in biomedical applications, however, current fabrication methods limit lipid microparticles to monolithic spherical shapes. This study presents calcium-based water-soluble 3D micro molds fabricated using two-photon polymerization

SUBMITTER: Park J 

PROVIDER: S-EPMC11836409 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature