In vitro protein expression profile of cultivated muscle cells from Labeo rohita.

ABSTRACT: A new cell line developed from the muscle tissue of L. rohita (LR) was utilized to understand the proteome in-depth. Comparative proteome analysis was performed for LR muscle cells at different passages (1, 15 and 25) using label free quantitative proteomics. A total of 138 proteins containing ≥ two unique peptides were used to assess expression at the different passages. Hierarchical clustering of the top 25 proteins with significant differences in abundances was plotted across the different passages with a fold-change of 1.5. Protein-protein interactions of significantly expressed proteins with respective KEGG pathways were represented using STRING. The metascape depicts the network of significantly enriched proteins with functional annotation of protein-encoding genes. Functional analys

SUBMITTER: Yashwanth BS 

PROVIDER: S-EPMC11836462 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature