Breast cancer shares many epidemiological, lifestyle, and local hormonal and metabolic underpinnings with endometrial and ovarian cancer: a narrative review.

ABSTRACT:

Background and objective

Breast, endometrial, and ovarian cancers (OCs) are significant public health concerns. Approximately three million patients are diagnosed with one of the three tumor types annually. The three tumor types exhibit related epidemiological trends, lifestyle risk factors, and tumor-specific characteristics which may influence their incidence and outcomes. While the majority of the literature examining hormone dependence of cancer appropriately is centered around breast cancer (BC), insufficient attention has been paid to how lessons from the biology of endometrial and OC may inform what we know about the biology of BC and vice versa. This narrative review seeks to address that unmet need.

Methods

The construction of this narrative review involved searchin

SUBMITTER: Rodriguez YM 

PROVIDER: S-EPMC11836739 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature