Underlying factors that affect ultrasound conspicuity of breast biopsy markers: an exploratory study.

ABSTRACT:

Background

During management of node-positive breast cancer, neoadjuvant systemic therapy (NST) is often used to de-escalate surgical intervention. To identify pathology-proven positive nodes regardless of visual changes after NST, breast biopsy clips or markers are inserted under ultrasound guidance as part of standard care, though most markers are used off-label in the axilla. However, clipped nodes may be difficult to visually confirm with ultrasound after a pathological complete response. This can affect the ease of executing subsequent procedures, such as surgical resection, because identifying the marked or clipped nodes in these cases is problematic. The mechanisms that affect these changes in clip conspicuity are poorly understood, making it challenging to improve ultrasoun

SUBMITTER: Cario J 

PROVIDER: S-EPMC11836746 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature