Neural Response to Food Cues in Avoidant/Restrictive Food Intake Disorder.

ABSTRACT:

Importance

The neurobiology of avoidant/restrictive food intake disorder (ARFID) is poorly understood.

Objective

To evaluate whether individuals with ARFID exhibit disruptions in fear, appetite, and disgust brain regions compared with healthy control (HC) participants when shown images of food and objects.

Design, setting, and participants

In this case-control study conducted from July 2016 to January 2021, children, adolescents, and young adults completed structured interviews and a validated functional magnetic resonance imaging (fMRI) food cue paradigm. The study was conducted at a single academic medical center. Data analysis was conducted from April 2023 to August 2024.

Exposures

Presence vs absence of ARFID and its phenotypes (ARFID-fear, ARFID-lack of in

SUBMITTER: Thomas JJ 

PROVIDER: S-EPMC11836757 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature