Peripandemic outcomes of infants treated for sentinel congenital heart diseases in England and Wales.

ABSTRACT:

Background

Infants with congenital heart disease (CHD) are clinically vulnerable to cardiac deteriorations and intercurrent infections. We aimed to quantify the impact of health system disruptions during the COVID-19 pandemic, on their clinical outcomes and whether these differed by socioeconomic and ethnic subgroups.

Methods

In this population-based cohort study, we used linked electronic healthcare datasets from England and Wales to identify infants with nine sentinel CHDs born and undergoing intervention in 2018-2022. The outcomes of cardiac intervention timing, infant mortality and hospital care utilisation, were described by birth eras, and risk factors were explored using multivariable regression.

Results

Of 4900 included infants, 1545 (31.5%) were born prepande

SUBMITTER: Huang Q 

PROVIDER: S-EPMC11836792 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature