Mechanical insufflation-exsufflation use in neuromuscular disease: a single centre cohort study.

ABSTRACT:

Introduction

Mechanical insufflation-exsufflation (MIE) is a commonly used therapy to augment secretion clearance in individuals with neuromuscular disease. There are no clear evidence-based guidelines on the settings that should be used in different diagnostic groups and how they should be titrated. We report on the settings used in the largest cohort of individuals using domiciliary MIE in the literature.

Methods

A retrospective observational study reporting on all individuals initiated on MIE for long-term domiciliary use at our centre, 2013-2019.

Results

This study reports on 359 adults established on domiciliary MIE. The most common diagnostic groups were congenital neuromuscular disease (26%), spinal cord injury (23%) and amyotrophic lateral sclerosis (23%). Med

SUBMITTER: Shah NM 

PROVIDER: S-EPMC11836793 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature