The Chemical Constituents and Anti-Hyperlipidemia Effect of Salt-Processed Fenugreek Seed.

ABSTRACT: The seed of fenugreek (FS) was traditionally used in diets and as a spice in India, as well as medicine in China. It had anti-diabetic and anti-hypolipidemic effects. According to the theory of traditional Chinese medicine, the effects of FS were enhanced after salt processing. But the enhanced effect of salt-processed fenugreek seed (SFS) on anti-hyperlipidemia was not yet fully understood. By UPLC-QTOF-MS analysis, five flavonoids and six saponins were tentatively identified in SFS. Salt processing increased the dissolution of polysaccharides and trigonelline. FS and SFS significantly improved the serum biochemical indexes, including total cholesterol (TC), triglycerides (TG), and low-density lipoprotein cholesterol (LDL-C) of hyperlipidemic rats, promoted the excretion of TC and total b

SUBMITTER: Qu Y 

PROVIDER: S-EPMC11837036 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature