A Novel Method for Assessing Cardiac Output With the Use of Oxygen Circulation Time.

ABSTRACT:

Background

We investigated whether a simple breath hold would yield dynamic oxygen (O₂) saturation change and whether the derived circulation time would be useful in assessing cardiac function.

Methods and results

Patients undergoing right heart catheterization for clinical indications (n = 48), including heart failure (HF; n = 24), were prospectively recruited. Each subject was instructed to hold their breath for 20-40 seconds. Lung to finger circulation time (LFCT), defined as the time from the point of rebreathing to nadir O₂ desaturation, was correlated with cardiac output. Among 48 subjects recruited, 37 manifested ≥3% O₂ desaturation allowing for an LFCT measurement. Mean LFCT was 38.5 ± 17.5 seconds (range 18.9-94.7 s). LFCT in patient

SUBMITTER: Kwon Y 

PROVIDER: S-EPMC11837221 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature