Global trends and risk factors of laryngeal cancer: a systematic analysis for the Global Burden of Disease Study (1990-2021).

ABSTRACT:

Introduction

This study aimed to explore the epidemiological trends of laryngeal cancer (LC) using the 2021 Global Burden of Disease (GBD) data.

Methods

We analyzed the global LC incidence, deaths, disability-adjusted life years (DALYs), and risk factors from 1990 to 2021. We evaluated trends using the annual percentage change (EAPC) and examined variations and associations in LC burden across regions, sociodemographic index (SDI) categories, and age groups.

Results

In 2021, the global age-standardized incidence rate (ASIR) for LC was 2.293 (95% UI: 2.133-2.466), the age-standardized death rate (ASDR) was 1.35 (1.259-1.449), and the age-standardized DALYs rate was 35.803 (33.294-38.538). The EAPCs for ASIR, ASDR, and age-standardized DALYs were -1.089, -1.659, and -1.

SUBMITTER: Zhou T 

PROVIDER: S-EPMC11837445 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature