Pre-pregnancy intrauterine device use is associated with a reduced risk of subsequent preterm birth: a large population-based cohort study.

ABSTRACT:

Background

The effect of pre-pregnancy intrauterine device (IUD) use on subsequent preterm birth (PTB) remains unclear. We aim to investigate the association between IUD use before pregnancy and subsequent PTB.

Methods

A total of 240,437 women who participated in the National Free Preconception Health Examination Project (NFPHEP) in Yunnan from 2013 to 2019 were included in the study. All study participants were classified into three groups according to their use of pre-pregnancy contraceptive methods: non-method users, IUD users, and other method users. We used a multivariable Poisson regression model to investigate the association between the use of an IUD before pregnancy and subsequent PTB. Further models analyzed the multiplicative and additive interactions between pre-

SUBMITTER: Chen X 

PROVIDER: S-EPMC11837476 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature