A novel FadL family outer membrane transporter is involved in the uptake of polycyclic aromatic hydrocarbons.

ABSTRACT: Gram-negative bacteria play a pivotal role in the bioremediation of persistent organic pollutants, such as polycyclic aromatic hydrocarbons (PAHs). Because the outer membrane (OM) of these bacteria hinders the direct permeation of hydrophobic substances into the cells, trans-OM proteins are required for the uptake of PAHs. However, neither the characteristics of PAH transporters nor the specific transport mechanism has been well interpreted. In this study, we revealed the participation of a novel FadL family transporter, PadL, in the biodegradation of the representative PAH phenanthrene in Novosphingobium pentaromativorans US6-1, an efficient PAH-degrading bacterium. PadL facilitates the cross-OM transport of phenanthrene, thus upregulating the expression of the gene ahdA1e t

SUBMITTER: Meng Q 

PROVIDER: S-EPMC11837497 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature