Quorum sensing regulates virulence factors in the coral pathogen <i>Vibrio coralliilyticus</i>.

ABSTRACT: The bacterial pathogen Vibrio coralliilyticus causes disease in coral species worldwide. The mechanisms of V. coralliilyticus coral colonization, coral microbiome interactions, and virulence factor production are understudied. In other model Vibrio species, virulence factors like biofilm formation, toxin secretion, and protease production are controlled through a density-dependent communication system called quorum sensing (QS). Comparative genomics indicated that V. coralliilyticus genomes share high sequence identity for most of the QS signaling and regulatory components identified in other Vibrio species. Here, we identify an active QS signaling pathway in two V. coralliilyticus strains with distinct infection etiologies: type strain BAA-450 and

SUBMITTER: Lydick VN 

PROVIDER: S-EPMC11837519 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature