Gene novelty and gene family expansion in the early evolution of Lepidoptera.

ABSTRACT:

Background

Almost 10% of all known animal species belong to Lepidoptera: moths and butterflies. To understand how this incredible diversity evolved we assess the role of gene gain in driving early lepidopteran evolution. Here, we compared the complete genomes of 115 insect species, including 99 Lepidoptera, to search for novel genes coincident with the emergence of Lepidoptera.

Results

We find 217 orthogroups or gene families which emerged on the branch leading to Lepidoptera; of these 177 likely arose by gene duplication followed by extensive sequence divergence, 2 are candidates for origin by horizontal gene transfer, and 38 have no known homology outside of Lepidoptera and possibly arose via de novo gene genesis. We focus on two new gene families that are conserved across

SUBMITTER: Hoile AE 

PROVIDER: S-EPMC11837612 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature