Phytochemical and antibacterial properties of calyces Hibiscus sabdariffa L.: an in vitro and in silico multitarget-mediated antibacterial study.

ABSTRACT:

Background

Multidrug-resistant (MDR) bacteria pose a significant threat to human health worldwide by increasing the harmful impact of traditional synthetic antibiotics. Traditional medicinal plants have bioactive metabolites that can significantly modulate the growth rate, cell survival, and pathogenicity of antibiotic-resistant bacteria. Hibiscus sabdariffa L., known as Roselle or Karkade, belongs to the Malvaceae family. It is well-known for its edible aromatic red/purple calyces and is extensively utilized in the food industry and pharmacological applications. H. sabdariffa calyx bioactive phytocompounds have potent therapeutic activities such as antimicrobial, antidiabetic, antiobesity, antioxidant, anti-inflammatory, and anticancer properties.

Methods

This study utilize

SUBMITTER: Ghaly HKF 

PROVIDER: S-EPMC11837655 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature