The GenderCOS project: study protocol for the development of two international Core Outcome Sets for genital gender affirming surgery.

ABSTRACT: Background: Worldwide an increasing number of transgender and gender diverse individuals are requesting genital Gender Affirming Surgery (gGAS). For both masculinizing and feminizing gGAS various procedures and techniques are employed. Current literature on gGAS reports heterogeneous, non-standardized and often ill-defined outcomes. Presently, no consensus exists on what outcomes should be evaluated in order to assess the clinical results and the effectiveness of these procedures, which precludes development of evidence-based treatment guidelines. Aims: This international consensus study aims to develop Core Outcome Sets (COS) for both masculinizing and feminizing gGAS. These represent the minimum sets of outcomes recommended to be measured and reported in all c

SUBMITTER: Roijer PJ 

PROVIDER: S-EPMC11837927 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature