Mosquito host background influences microbiome-ZIKV interactions in field and laboratory-reared <i>Aedes aegypti</i>.

ABSTRACT: The mosquito microbiota represents an intricate assemblage of microorganisms, comprising bacteria, fungi, viruses, and protozoa. Factors modulating microbiome abundance and composition include host genetic background, environmental parameters, and pathogen exposure. Conversely, the microbiome profoundly influences pathogen infection of the mosquito host and thus harbours considerable potential to impact the transmission of vector-borne diseases. As such, there is a growing interest in using the microbiome in novel vector-control strategies, including exploiting the natural ability of some microbes to interfere with infection of the vectors by pathogens. However, before novel microbiome-based vector control approaches can move towards translation, a more complete understanding of the intera

SUBMITTER: Cansado-Utrilla C 

PROVIDER: S-EPMC11838435 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature