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Constipation and risk of death and cardiovascular events in patients on hemodialysis.


ABSTRACT:

Background

Constipation is a common gastrointestinal disorder and is often accompanied by alteration in the gut microbiota. Recently, several studies have disclosed its association with an increased risk of cardiovascular disease and mortality in the general population. Despite the high prevalence of constipation, data on the clinical impact of constipation in patients with chronic kidney disease are limited. We aimed to explore the prevalence of constipation and its association with cardiovascular disease in chronic kidney disease using a nationally representative cohort of hemodialysis patients.

Methods

This study used hemodialysis quality assessment and health insurance claims data from patients undergoing maintenance hemodialysis in South Korea. Chronic constipation was

SUBMITTER: Park SC 

PROVIDER: S-EPMC11838856 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature