The influence of fetal sex on maternal blood pressure in pregnancy.

ABSTRACT:

Background

Pregnancy with a male fetus carries a higher risk of term pre-eclampsia than pregnancy with a female fetus. Based on evidence that maternal blood pressure (BP) may be raised in pregnancies with Beckwith-Wiedemann syndrome (fetal overgrowth), a possible contributing factor to the association between male sex and term pre-eclampsia is that males grow faster, reaching ~130 g higher birth weight, on average, than females. The association between fetal sex and maternal BP in healthy pregnancies is not known. We hypothesized that male sex would be associated with higher maternal BP in healthy pregnancies, and that this association would be explained by birth weight differences between males and females.

Methods and findings

We tested the association between fetal sex an

SUBMITTER: Decina CS 

PROVIDER: S-EPMC11839000 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature