Striatal and cerebellar interactions during reward-based motor performance.

ABSTRACT: Goal-directed motor performance relies on the brain's ability to distinguish between actions that lead to successful and unsuccessful outcomes. The basal ganglia (BG) and cerebellum (CBL) are integral to processing performance outcomes, yet their functional interactions remain underexplored. This study scanned participants' brains with functional magnetic imaging (fMRI) while they performed a skilled motor task for monetary rewards, where outcomes depended on their motor performance and also probabilistic events that were not contingent on their performance. We found successful motor outcomes increased activity in the ventral striatum (VS), a functional sub-region of the BG, whereas unsuccessful motor outcomes engaged the CBL. In contrast, for probabilistic outcomes unrelated to motor perf

SUBMITTER: Lee JL 

PROVIDER: S-EPMC11839110 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature