East and South Asian-Specific Blood Pressure Trajectories and Cardiovascular Disease.

ABSTRACT:

Background

Cardiovascular disease (CVD) risk differs across Asian subgroups, possibly due to differences in hypertension burden. We characterized lifetime blood pressure (BP) trajectories for East and South Asian individuals and compared their associations with CVD risk.

Methods

Among 148 872 UK Biobank participants with primary care utilization data, life course BP trajectories were fitted as a function of age by sex according to self-identified ethnicity. We determined associations of time-averaged young adulthood (18-39 years), middle age (40-64 years), and later life (≥65 years) systolic BP (SBP) and diastolic BP with incident atherosclerotic CVD risk.

Results

The predicted SBP/diastolic BP (95% CI) at age 30 years was 108 (103-114)/68 (65-71) mm Hg for East Asian

SUBMITTER: Cho SMJ 

PROVIDER: S-EPMC11839333 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature