Skin microbiome differences in pancreatic adenocarcinoma, other cancers, and healthy controls: a pilot study.

ABSTRACT:

Introduction

Many studies have reported the importance of the human microbiome in relationship to the overall health of its host. While recent studies have explored the microbiome's role in various types of cancer compared to healthy patients, this pilot study is the first to investigate differences in the skin microbiome composition among pancreatic adenocarcinoma patients, individuals with other cancers, and cancer-free controls.

Methods

The study characterizes the skin microbiome's potential associations with cancer status by analyzing skin swabs from the forehead and cheek of 58 participants using Next Generation Sequencing (NGS), differential abundance analysis, and machine learning techniques.

Results

The study results indicated that the cancer group displayed a

SUBMITTER: Davis T 

PROVIDER: S-EPMC11839409 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature