Patient and Family Caregiver Perspectives on Therapy De-Escalation in Cancer: A Scoping Review.

ABSTRACT:

Background

Cancer therapy de-escalation aims to reduce treatment intensity, minimizing the burden of short- and long-term toxicities on patients and family caregivers while maintaining current survival rates. While this approach holds potential benefits, it comes at a risk of worse patient health outcomes or treatment failure. An understanding of patient and family caregiver perspectives regarding cancer therapy de-escalation is required to design successful patient-and-caregiver-informed clinical trials, and optimally provide related patient-centered care.

Aim

To identify and synthesize the literature about patient and family caregiver perspectives of cancer therapy de-escalation to guide clinical care, research, decision-support resources, and education.

Methods

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SUBMITTER: Hamilton R 

PROVIDER: S-EPMC11839414 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature