Association between magnesium depletion score and prevalence of hyperuricemia in American adults: a study based on NHANES 2007-2018.

ABSTRACT:

Background

The Magnesium Depletion Score (MDS) is a novel indicator that integrates multiple factors to assess systemic magnesium depletion. However, its association with hyperuricemia (HUA) prevalence remains unclear. This study aims to investigate the relationship between MDS and the prevalence of HUA.

Methods

A cross-sectional analysis was conducted using data from the 2007-2018 National Health and Nutrition Examination Survey (NHANES). The MDS was derived by integrating multiple risk factors associated with magnesium depletion: the use of diuretics and proton pump inhibitors (PPI), estimated glomerular filtration rate (eGFR), and alcohol consumption exceeding recommended thresholds. Univariable and multivariable logistic regression models assessed the association between

SUBMITTER: Xiao Y 

PROVIDER: S-EPMC11839436 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature