Reduced-energy diet in women with gestational diabetes: the dietary intervention in gestational diabetes DiGest randomized clinical trial.

ABSTRACT: Reduced-energy diets promote weight loss and improve long-term outcomes in type 2 diabetes but are untested in gestational diabetes. We aimed to identify if weight loss in pregnancy improves perinatal outcomes in gestational diabetes. We performed a multicentre parallel, randomized, controlled, double-blind trial of energy restriction in women with singleton pregnancies, gestational diabetes and body mass index ≥25 kg m^-2. Participants were randomized to receive a standard-energy control diet (2,000 kcal d^-1) or reduced-energy intervention diet (1,200 kcal d^-1) from enrollment (29 weeks) until delivery, provided as weekly diet boxes (40% carbohydrate, 35% fat, 25% protein). The randomization was performed in a 1:1 ratio, stratified by center and

SUBMITTER: Kusinski LC 

PROVIDER: S-EPMC11839452 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature