Perturbations in gut microbiota composition in patients with autoimmune neurological diseases: a systematic review and meta-analysis.

ABSTRACT: Studies suggest that gut dysbiosis occurs in autoimmune neurological diseases, but a comprehensive synthesis of the evidence is lacking. Our aim was to systematically review and meta-analyze the correlation between the gut microbiota and autoimmune neurological disorders to inform clinical diagnosis and therapeutic intervention. We searched the databases of PubMed, Embase, Web of Science, and the Cochrane Library until 1 March 2024 for research on the correlation between gut microbiota and autoimmune neurological disorders. A total of 62 studies provided data and were included in the analysis (n = 3,126 patients, n = 2,843 healthy individuals). Among the included studies, 42 studies provided data on α-diversity. Regarding α-diversity, except for Chao1, which showed a consiste

SUBMITTER: Deng X 

PROVIDER: S-EPMC11839609 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature