Loudness dependence of the auditory evoked potential: temporal stability, associations to sociodemographic variables, and functional significance-implications for clinical research.

ABSTRACT:

Introduction

The loudness dependence of the auditory evoked potential (LDAEP) has been suggested as a biomarker for central serotonergic function, and as such a proxy for serotonin related psychiatric symptomatology and intervention outcome, particularly in depression. This study aims to explore LDAEP characteristics in a large healthy population by assessing its test-retest reliability and examining associations with sociodemographic variables, psychological distress, and performance-based cognitive function.

Methods

Our sample included 100 healthy adults whose LDAEP was measured and correlated with age, sex, self-reported psychological distress, and cognitive performance.

Results

Participants examined twice (n = 38) showed high test-retest reliability with in

SUBMITTER: Andersson S 

PROVIDER: S-EPMC11839817 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature