Paraben exposure related to Staphylococcal enterotoxin IgE sensitization, allergic rhinitis and nasal patency in children.

ABSTRACT: The study aims to investigate the link between paraben exposure, Staphylococcal enterotoxin IgE sensitization, and their combined relationship on allergic rhinitis and nasal patency in children. We assessed 276 children aged 10-12, examining their demographic backgrounds, atopy status, prevalence of allergic diseases, and serum specific IgE levels for Staphylococcal enterotoxins A, B, and toxic shock syndrome toxin (TSST). Parabens metabolites in urine samples were measured to assess exposure levels. The cohort included 276 children (mean 10.9 years), comprising 119 males and 157 females. Of these, 157 children (57.7%) were diagnosed with allergic rhinitis, 44 (15.9%) tested positive for Staphylococcal enterotoxins A, 33 (12.0%) for Staphylococcal enterotoxins B, and 94 (34.1%) for TSST. P

SUBMITTER: Ha EK 

PROVIDER: S-EPMC11839920 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature