Perceptions of severity and their influence on reproductive decision-making following reproductive genetic carrier screening.

ABSTRACT: The concept of severity in healthcare is multidimensional and subjective. It is a primary consideration in reproductive genetic carrier screening design where the focus is providing reproductive couples with information about the chance of severe genetic conditions in their offspring. When offering this screening, it is important to understand how condition severity is perceived and incorporated into reproductive decision-making. We analysed data from 41 semi-structured interviews with people who received a screening result indicating an increased chance for having children with a genetic condition. Thematic analysis revealed a desire for comprehensive information about the condition including clinical features, prognosis, impact on quality of life and treatment/management options. Partici

SUBMITTER: Swainson E 

PROVIDER: S-EPMC11839978 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature