Association between blood eosinophil levels and prognosis in critically ill patients with different heart failure phenotypes.

ABSTRACT: Heart failure (HF) is associated with poor prognosis. While various immune markers have been linked to HF outcomes, the relationship between eosinophils (EOS) and prognosis across different HF phenotypes remains unclear and controversial. In this study, we analyzed 2,677 HF patients from the Medical Information Mart for Intensive Care III (MIMIC-III) database, categorizing them into reduced ejection fraction (≤ 50%) and preserved ejection fraction (> 50%) groups. Multiple logistic regression, Kaplan-Meier survival curve estimation, Cox proportional hazards model, and restricted cubic splines were employed to assess the association between admission EOS and mortality. Subgroup analyses were conducted based on age, gender, sepsis, atrial fibrillation, hypertension and rheumatic and immunolog

SUBMITTER: Guan C 

PROVIDER: S-EPMC11840013 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature