Partial or focal brachytherapy for prostate cancer: a systematic review and meta-analysis.

ABSTRACT:

Objectives

Recent advances in image-guided brachytherapy have allowed for treatment volume reduction in the treatment of prostate cancer, with the aim to optimize disease control and reduce toxicities. This systematic review reports on the efficacy and safety of focal brachytherapy for treatment of patients with localized prostate cancer.

Methods

Medline, Embase, Web of Science, and Cochrane were searched from inception to July 2023. Studies were included if they reported on focal brachytherapy, and described either dosimetry or clinical outcomes in the monotherapy or salvage setting. Meta-analysis was conducted to estimate biochemical control (BC) at 12-60 months. The review protocol was registered on PROSPERO (CRD42022320921).

Results

Twenty-six studies reporting on

SUBMITTER: Gutierrez-Valencia E 

PROVIDER: S-EPMC11840170 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature