A simplified online adaptive workflow for long-course magnetic resonance-guided radiotherapy in esophageal cancer.

ABSTRACT:

Background and purpose

Online adaptive magnetic resonance-guided radiotherapy (MRgRT) enables high-precision radiotherapy for esophageal cancer patients but is less feasible due to long on-table times in combination with long-course treatment. In this study, we conducted an in-silico assessment of a simplified online adaptive workflow, Adapt-To-Shape-lite (ATS-lite), in which deformable propagated contours are not modified, and assessed its feasibility.

Materials and methods

The ATS-lite workflow was simulated for all fractions of nine esophageal cancer patients who had previously received full online adaptive MRgRT with manual contour corrections if needed. The deformable propagated contours were not adjusted. A dose of 41.4 Gy in 23 fractions was prescribed. Intra- and int

SUBMITTER: Kuijer KM 

PROVIDER: S-EPMC11840183 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature