Global burden of metabolic dysfunction-associated steatotic liver disease, 2010 to 2021.

ABSTRACT:

Background & aims

This study used the Global Burden of Disease data (2010-2021) to analyze the rates and trends of point prevalence, annual incidence, and years lived with disability (YLDs) for metabolic dysfunction-associated steatotic liver disease (MASLD) in 204 countries.

Methods

Total numbers and age-standardized rates per 100,000 population for MASLD prevalence, annual incidence, and YLDs were compared across regions and countries by age, sex, and sociodemographic index (SDI). Smoothing spline models were used to evaluate the relationship between the burden of MASLD and SDI. Estimates were reported with uncertainty intervals (UI).

Results

Globally, in 2021, the age-standardized rates per 100,000 population of point prevalence of MASLD were 15,018.1 cases (95% UI

SUBMITTER: Feng G 

PROVIDER: S-EPMC11840544 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature