Risk of Cardiovascular Morbidity and Mortality in Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Survivors.

ABSTRACT:

Importance

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) cause diffuse epidermal detachment and necrosis. Patients who survive the initial SJS/TEN episodes are affected by various sequelae.

Objective

To investigate the risks of cardiovascular morbidity and mortality in SJS/TEN survivors.

Design, setting, and participants

This was a nationwide population-based cohort study using data from Taiwan's National Health Research Institute Database linked to the National Register of Death databases for 1998 to 2021. Survivors of SJS/TEN were identified and matched with non-SJS/TEN participants by age, sex, and Charlson Comorbidity Index. Data analysis was performed from November 2023 to June 2024.

Exposure

Cerebrovascular accidents (CVA) or ischemi

SUBMITTER: Chiu HY 

PROVIDER: S-EPMC11840681 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature