Mohs Surgery vs Wide Local Excision in Primary High-Stage Cutaneous Squamous Cell Carcinoma.

ABSTRACT:

Importance

High-stage cutaneous squamous cell carcinoma (cSCC) has an increased risk of recurrence, metastasis, and mortality. Studies investigating the outcomes of high-stage cSCC among patients treated with Mohs surgery compared with those treated with wide local excision (WLE) are limited.

Objective

To assess the outcomes of primary high-stage cSCC among patients treated with Mohs surgery compared with those treated with WLE.

Design, setting, and participants

This retrospective cohort study using propensity score weighting was conducted in a tertiary academic medical center in Boston, Massachusetts. Patients were included if they had primary high-stage cSCC and had been treated with either Mohs surgery or WLE between January 1, 2000, and December 31, 2019. Data ana

SUBMITTER: Wang DM 

PROVIDER: S-EPMC11840687 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature