National Trends in Chronic Rhinosinusitis and Inpatient Sinus Surgery in Adults with Cystic Fibrosis.

ABSTRACT:

Objective

Given the recent dramatic changes in medical therapy for cystic fibrosis (CF), this study aims to describe temporal changes in chronic rhinosinusitis (CRS) and endoscopic sinus surgery (ESS) rates.

Methods

National Inpatient Sample (2004-2019; weighted estimates for 119,067 pediatric and 202,407 adult patients) was used to analyze adult (age ≥18 years) and pediatric patients with CF with pulmonary manifestations. Comorbid CRS, ESS rates, and extended length of stay (LOS, ≥75th percentile) were analyzed.

Results

The rate of CRS in both pediatric (14.1% vs 21.1%, P < .001) and adult (16.5% vs 40.9%, P < .001) patients increased. Rate of ESS in pediatric patients with CRS decreased from 25.3% to 3.4% (P < .001). A similar decline occurred i

SUBMITTER: Qu RW 

PROVIDER: S-EPMC11840695 | biostudies-literature | 2025 Jan-Mar

REPOSITORIES: biostudies-literature