Rare Chlorinated Fungal Metabolite and Alpha-Pyrones from an Endophytic Fungus Nigrospora sp.

ABSTRACT: Endophytic microorganisms have been recognized as potential sources of new chemical entities with applications in the pharmaceutical, biotechnology, agricultural, and other industries. This study investigated the secondary metabolites produced by an endophytic Nigrospora sp. isolated from the Nigerian plant, Gongronema latifolium. Standard procedures were followed for fungal isolation, taxonomic identification, fermentation, and extraction of secondary metabolites. The antioxidant and antimicrobial properties of the fungal extract were assessed using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) antioxidant assay and the agar-well diffusion assay, respectively. Various chromatographic and spectroscopic techniques were used to isolate, purify, and characterize compounds from the fungal ex

SUBMITTER: Abba CC 

PROVIDER: S-EPMC11840770 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature