Automated Insulin Delivery in Older Adults with Type 1 Diabetes.

ABSTRACT:

Background

Older adults with type 1 diabetes are at risk for serious hypoglycemia. Automated insulin delivery can reduce risk but has not been sufficiently evaluated in this population.

Methods

We conducted a multicenter, randomized crossover trial in adults older than or equal to 65 years of age with type 1 diabetes. Participants completed three 12-week periods of using hybrid closed loop, predictive low-glucose suspend, and sensor-augmented pump insulin delivery in a randomized order. The primary outcome was the percentage of time with continuous glucose monitoring glucose values less than 70 mg/dl.

Results

Eighty-two participants between 65 and 86 years of age were randomly assigned: 45% were female; the baseline mean (±SD) glycated hemoglobin level was 7.2±0.9%; a

SUBMITTER: Kudva YC 

PROVIDER: S-EPMC11840810 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature