A supply-based scoring approach to account for biological disadvantages in accessing lung transplant.

ABSTRACT:

Background

The lung Composite Allocation Score (CAS) accounts separately for biological disadvantages stemming from candidate blood type and height using consensus-derived heuristics, which do not reflect the true supply of compatible organs available to candidates with specific combinations of blood type and height. Here, we develop an alternative CAS biological disadvantages subscore using a novel measure of donor supply.

Methods

Using Scientific Registry of Transplant Recipients data from February 19, 2015 to September 1, 2021, we modeled daily distance-adjusted supply of compatible donors, as a function of candidate blood type, height, and diagnosis group, using Poisson rate regression and applied the model to create a 10-point supply-based subscore. Substituting this su

SUBMITTER: Rose J 

PROVIDER: S-EPMC11840864 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature